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Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death

Mitochondria are best known as the essential intracellular organelles that host the homeostasis required for cellular survival, but they also have relevance in diverse disease-related conditions, including Alzheimer's disease (AD). Amyloid β (Aβ) peptide is the key molecule in AD pathogenesis,...

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Autori principali: Cha, Moon-Yong, Han, Sun-Ho, Son, Sung Min, Hong, Hyun-Seok, Choi, Young-Ju, Byun, Jayoung, Mook-Jung, Inhee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325919/
https://ncbi.nlm.nih.gov/pubmed/22514691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034929
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