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Amyloid β‐induced elevation of O‐GlcNAcylated c‐Fos promotes neuronal cell death

Alzheimer's disease (AD) is an age‐related neurodegenerative disease characterized by progressive memory loss resulting from cumulative neuronal cell death. O‐linked β‐N‐acetyl glucosamine (O‐GlcNAc) modification of the proteins reflecting glucose metabolism is altered in the brains of patients...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Choi, Heesun, Kim, Chaeyoung, Song, Hyundong, Cha, Moon‐Yong, Cho, Hyun Jin, Son, Sung Min, Kim, Haeng Jun, Mook‐Jung, Inhee
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351842/
https://ncbi.nlm.nih.gov/pubmed/30515991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12872
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