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Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS

BACKGOUND: Amyotrophic lateral sclerosis (ALS) is progressive neurodegenerative disease characterized by the loss of motor function. Several ALS genes have been identified as their mutations can lead to familial ALS, including the recently reported RNA-binding protein fused in sarcoma (Fus). However...

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Bibliografiske detaljer
Main Authors: Xia, Ruohan, Liu, Yajuan, Yang, Liuqing, Gal, Jozsef, Zhu, Haining, Jia, Jianhang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325858/
https://ncbi.nlm.nih.gov/pubmed/22443542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-10
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