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The ALS gene FUS regulates synaptic transmission at the Drosophila neuromuscular junction

Mutations in the RNA binding protein Fused in sarcoma (FUS) are estimated to account for 5–10% of all inherited cases of amyotrophic lateral sclerosis (ALS), but the function of FUS in motor neurons is poorly understood. Here, we investigate the early functional consequences of overexpressing wild-t...

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Detalhes bibliográficos
Main Authors: Machamer, James B., Collins, Sarah E., Lloyd, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065154/
https://ncbi.nlm.nih.gov/pubmed/24569165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu094
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