Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled

Wnt binding to members of the seven-span transmembrane Frizzled (Fz) receptor family controls essential cell fate decisions and tissue polarity during development and in adulthood. The Fz-mediated membrane recruitment of the cytoplasmic effector Dishevelled (Dvl) is a critical step in Wnt/β-catenin...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Tauriello, Daniele V. F., Jordens, Ingrid, Kirchner, Katharina, Slootstra, Jerry W., Kruitwagen, Tom, Bouwman, Britta A. M., Noutsou, Maria, Rüdiger, Stefan G. D., Schwamborn, Klaus, Schambony, Alexandra, Maurice, Madelon M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
Onderwerpen:
PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325702/
https://ncbi.nlm.nih.gov/pubmed/22411803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114802109
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items