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Antigen-specific antibody responses in B-1a and their relationship to natural immunity
B-1a cells are primarily thought of as natural antibody-producing cells. However, we now show that appropriate antigenic stimulation induces IgM and IgG B-1a antibody responses and long-lived T-independent antigen-specific B-1a memory that differs markedly from canonical B-2 humoral immunity. Thus,...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325670/ https://ncbi.nlm.nih.gov/pubmed/22421134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121631109 |
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