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Distinct B-cell lineage commitment distinguishes adult bone marrow hematopoietic stem cells

The question of whether a single hematopoietic stem cell (HSC) gives rise to all of the B-cell subsets [B-1a, B-1b, B-2, and marginal zone (MZ) B cells] in the mouse has been discussed for many years without resolution. Studies here finally demonstrate that individual HSCs sorted from adult bone mar...

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Autors principals: Ghosn, Eliver Eid Bou, Yamamoto, Ryo, Hamanaka, Sanae, Yang, Yang, Herzenberg, Leonard A., Nakauchi, Hiromitsu, Herzenberg, Leonore A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325648/
https://ncbi.nlm.nih.gov/pubmed/22431624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121632109
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