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Division and differentiation of natural antibody-producing cells in mouse spleen

B-1a cells reside in both the peritoneal cavity and the spleen. LPS stimulates splenic B-1a to differentiate to plasma cells producing natural IgM specific for microbial and self antigens. However, there are conflicting views as to whether the B-1a cells divide before this differentiation occurs, an...

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Detalhes bibliográficos
Main Authors: Yang, Yang, Tung, James W., Ghosn, Eliver E. B., Herzenberg, Leonard A., Herzenberg, Leonore A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838637/
https://ncbi.nlm.nih.gov/pubmed/17360560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700001104
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