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Regulation of APC/C(Cdc20) activity by RASSF1A–APC/C(Cdc20) circuitry
RASSF1A is a key tumor-suppressor gene that is often inactivated in a wide variety of solid tumors. Studies have illustrated that RASSF1A plays vital roles in the regulation of cell-cycle progression and functions as a guardian of mitosis. Nevertheless, the precise mechanism of RASSF1A-dependent reg...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325600/ https://ncbi.nlm.nih.gov/pubmed/21874044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.372 |
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