DNA methylation status of REIC/Dkk-3 gene in human malignancies

PURPOSE: The REIC (reduced expression in immortalized cells)/Dkk-3 is down-regulated in various cancers and considered to be a tumor suppressor gene. REIC/Dkk-3 mRNA has two isoforms (type-a,b). REIC type-a mRNA has shown to be a major transcript in various cancer cells, and its promoter activity wa...

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Bibliografiske detaljer
Main Authors: Hayashi, Tatsuro, Asano, Hiroaki, Toyooka, Shinichi, Tsukuda, Kazunori, Soh, Junichi, Shien, Tadahiko, Taira, Naruto, Maki, Yuho, Tanaka, Norimitsu, Doihara, Hiroyoshi, Nasu, Yasutomo, Huh, Nam-ho, Miyoshi, Shinichiro
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325424/
https://ncbi.nlm.nih.gov/pubmed/22274868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-012-1158-6
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