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DNA methylation status of REIC/Dkk-3 gene in human malignancies
PURPOSE: The REIC (reduced expression in immortalized cells)/Dkk-3 is down-regulated in various cancers and considered to be a tumor suppressor gene. REIC/Dkk-3 mRNA has two isoforms (type-a,b). REIC type-a mRNA has shown to be a major transcript in various cancer cells, and its promoter activity wa...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer-Verlag
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325424/ https://ncbi.nlm.nih.gov/pubmed/22274868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-012-1158-6 |
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