RNA–protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNA
Ribozyme activity in vivo depends on achieving high-level expression, intracellular stability, target colocalization, and cleavage site access. At present, target site selection is problematic because of unforeseeable secondary and tertiary RNA structures that prevent cleavage. To overcome this desi...
保存先:
| 出版年: | Proc Natl Acad Sci U S A |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2001
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11344300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.091411398 |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|