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The role of distinct p185(neu) extracellular subdomains for dimerization with the epidermal growth factor (EGF) receptor and EGF-mediated signaling

The extracellular domain of p185(c-neu) can be viewed as a complex structure of four subdomains, two of which are cysteine-rich subdomains. We have investigated the contribution of these distinct p185(c-neu) extracellular subdomains to p185/epidermal growth factor receptor (EGFR) heteromer formation...

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Библиографические подробности
Главные авторы: Kumagai, Toru, Davis, James G., Horie, Takeo, O'Rourke, Donald M., Greene, Mark I.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC33246/
https://ncbi.nlm.nih.gov/pubmed/11320205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071060598
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