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High expression of p16(INK4a) and low expression of Bmi1 are associated with endothelial cellular senescence in the human cornea

PURPOSE: Determine cyclin-dependent kinase inhibitor 2A (p16(Ink4a)) and polycomb ring finger oncogene (Bmi1) expression in corneal endothelium samples from different age groups and test whether the expression of p16(INK4a) and Bmi1 are associated with endothelial cellular senescence in human cornea...

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Detalhes bibliográficos
Main Authors: Wang, Ye, Zang, Xinjie, Wang, Yao, Chen, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324359/
https://ncbi.nlm.nih.gov/pubmed/22509111
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