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Expression of senescence-related genes in human corneal endothelial cells

PURPOSE: To investigate the expression of p16(INK4a), p21(WAF1/CIP1), p27(KIP1), and p53 in human corneal endothelial cell (HCEC) senescence ex vivo at various donor ages. METHODS: Residual corneal tissues obtained after penetrating keratoplasty were used in this study. Age, death-to-preservation in...

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Bibliografiske detaljer
Main Authors: Song, Zhenhua, Wang, Ye, Xie, Lixin, Zang, Xinjie, Yin, Hongmei
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254959/
https://ncbi.nlm.nih.gov/pubmed/18334933
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