Inhibition of VEGF expression and corneal neovascularization by shRNA targeting HIF-1α in a mouse model of closed eye contact lens wear

PURPOSE: Inappropriate contact lens (CL) use and care often lead to corneal neovascularization (corneal NV). We used mouse eyes which wore CL as the animal model to assess the reason for corneal NV with CL wear. The similar and overlapping activity of vascular endothelial growth factor (VEGF) and th...

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Bibliografski detalji
Glavni autori: Chen, Peng, Yin, Hongmei, Wang, Ye, Wang, Yao, Xie, Lixin
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327437/
https://ncbi.nlm.nih.gov/pubmed/22511848
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