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RASSF1A and the Taxol Response in Ovarian Cancer
The RASSF1A tumor suppressor gene is frequently inactivated by promoter methylation in human tumors. The RASSF1A protein forms an endogenous complex with tubulin and promotes the stabilization of microtubules. Loss of RASSF1A expression sensitizes cells to microtubule destabilizing stimuli. We have...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Hindawi Publishing Corporation
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324163/ https://ncbi.nlm.nih.gov/pubmed/22548172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/263267 |
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