RASSF1A and the rs2073498 Cancer Associated SNP

RASSF1A is one of the most frequently inactivated tumor suppressors yet identified in human cancer. It is pro-apoptotic and appears to function as a scaffolding protein that interacts with a variety of other tumor suppressors to modulate their function. It can also complex with the Ras oncoprotein a...

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Bibliografiske detaljer
Main Authors: Donninger, Howard, Barnoud, Thibaut, Nelson, Nick, Kassler, Suzanna, Clark, Jennifer, Cummins, Timothy D., Powell, David W., Nyante, Sarah, Millikan, Robert C., Clark, Geoffrey J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Research Foundation 2011
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355887/
https://ncbi.nlm.nih.gov/pubmed/22649770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2011.00054
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