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Mitochondrial pathway of apoptosis is ancestral in metazoans
The mitochondrial pathway of apoptosis is the major mechanism of physiological cell death in vertebrates. In this pathway, proapoptotic members of the Bcl-2 family cause mitochondrial outer membrane permeabilization (MOMP), allowing the release of cytochrome c, which interacts with Apaf-1 to trigger...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324028/ https://ncbi.nlm.nih.gov/pubmed/22416118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120680109 |
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