Mitochondrial pathway of apoptosis is ancestral in metazoans

The mitochondrial pathway of apoptosis is the major mechanism of physiological cell death in vertebrates. In this pathway, proapoptotic members of the Bcl-2 family cause mitochondrial outer membrane permeabilization (MOMP), allowing the release of cytochrome c, which interacts with Apaf-1 to trigger...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bender, Cheryl E., Fitzgerald, Patrick, Tait, Stephen W. G., Llambi, Fabien, McStay, Gavin P., Tupper, Douglas O., Pellettieri, Jason, Alvarado, Alejandro Sánchez, Salvesen, Guy S., Green, Douglas R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324028/
https://ncbi.nlm.nih.gov/pubmed/22416118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120680109
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