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The ErbB4 extracellular region retains a tethered-like conformation in the absence of the tether
The epidermal growth factor receptor (EGFR) and its homologs ErbB3 and ErbB4 adopt a tethered conformation in the absence of ligand in which an extended hairpin loop from domain II contacts the juxtamembrane region of domain IV and tethers the domain I/II pair to the domain III/IV pair. By burying t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323790/ https://ncbi.nlm.nih.gov/pubmed/22012915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.753 |
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