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The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand
The human ErbB family of receptor tyrosine kinases comprises the epidermal growth factor receptor (EGFR/ErbB1/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). ErbBs play fundamental roles in cell growth and differentiation events in embryonic and adult tissues, and inappropriate ErbB activit...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1257738/ https://ncbi.nlm.nih.gov/pubmed/16203964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507591102 |
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