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The Role of Osteopontin and Osteopontin Aptamer (OPN-R3) in Fibroblast Activity
BACKGROUND: Scarring is believed to be caused by both persistent inflammation and overexuberant fibroblast activation. Osteopontin (OPN) is a cytokine that promotes cell activation. The absence of OPN in vivo reduces dermal scarring. This suggests that OPN is involved in scar formation; however, how...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323744/ https://ncbi.nlm.nih.gov/pubmed/21962803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2011.07.054 |
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