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The Role of Osteopontin and Osteopontin Aptamer (OPN-R3) in Fibroblast Activity

BACKGROUND: Scarring is believed to be caused by both persistent inflammation and overexuberant fibroblast activation. Osteopontin (OPN) is a cytokine that promotes cell activation. The absence of OPN in vivo reduces dermal scarring. This suggests that OPN is involved in scar formation; however, how...

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Detalhes bibliográficos
Main Authors: Hunter, Cedric, Bond, Jennifer, Kuo, Paul C., Selim, M. Angelica, Levinson, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323744/
https://ncbi.nlm.nih.gov/pubmed/21962803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2011.07.054
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