The Role of Osteopontin (OPN/SPP1) Haplotypes in the Susceptibility to Crohn's Disease

BACKGROUND: Osteopontin represents a multifunctional molecule playing a pivotal role in chronic inflammatory and autoimmune diseases. Its expression is increased in inflammatory bowel disease (IBD). The aim of our study was to analyze the association of osteopontin (OPN/SPP1) gene variants in a larg...

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Bibliographic Details
Main Authors: Glas, Jürgen, Seiderer, Julia, Bayrle, Corinna, Wetzke, Martin, Fries, Christoph, Tillack, Cornelia, Olszak, Torsten, Beigel, Florian, Steib, Christian, Friedrich, Matthias, Diegelmann, Julia, Czamara, Darina, Brand, Stephan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248444/
https://ncbi.nlm.nih.gov/pubmed/22242114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029309
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