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IRGM Variants and Susceptibility to Inflammatory Bowel Disease in the German Population

BACKGROUND & AIMS: Genome-wide association studies identified the autophagy gene IRGM to be strongly associated with Crohn's disease (CD) but its impact in ulcerative colitis (UC), its phenotypic effects and potential epistatic interactions with other IBD susceptibility genes are less clear...

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Detalhes bibliográficos
Main Authors: Glas, Jürgen, Seiderer, Julia, Bues, Stephanie, Stallhofer, Johannes, Fries, Christoph, Olszak, Torsten, Tsekeri, Eleni, Wetzke, Martin, Beigel, Florian, Steib, Christian, Friedrich, Matthias, Göke, Burkhard, Diegelmann, Julia, Czamara, Darina, Brand, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554777/
https://ncbi.nlm.nih.gov/pubmed/23365659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054338
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