Intestinal DMBT1 Expression Is Modulated by Crohn’s Disease-Associated IL23R Variants and by a DMBT1 Variant Which Influences Binding of the Transcription Factors CREB1 and ATF-2

OBJECTIVES: DMBT is an antibacterial pattern recognition and scavenger receptor. In this study, we analyzed the role of DMBT1 single nucleotide polymorphisms (SNPs) regarding inflammatory bowel disease (IBD) susceptibility and examined their functional impact on transcription factor binding and down...

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Main Authors: Diegelmann, Julia, Czamara, Darina, Le Bras, Emmanuelle, Zimmermann, Eva, Olszak, Torsten, Bedynek, Andrea, Göke, Burkhard, Franke, Andre, Glas, Jürgen, Brand, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818382/
https://ncbi.nlm.nih.gov/pubmed/24223725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077773
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