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Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis()
Human frataxin (FXN) has been intensively studied since the discovery that the FXN gene is associated with the neurodegenerative disease Friedreich’s ataxia. Human FXN is a component of the NFS1-ISD11-ISCU2-FXN (SDUF) core Fe-S assembly complex and activates the cysteine desulfurase and Fe-S cluster...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323110/ https://ncbi.nlm.nih.gov/pubmed/22352884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201628j |
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