Hypermethylated in Cancer 1 (HIC1) Recruits Polycomb Repressive Complex 2 (PRC2) to a Subset of Its Target Genes through Interaction with Human Polycomb-like (hPCL) Proteins

HIC1 (hypermethylated in cancer 1) is a tumor suppressor gene epigenetically silenced or deleted in many human cancers. HIC1 is involved in regulatory loops modulating p53- and E2F1-dependent cell survival, growth control, and stress responses. HIC1 is also essential for normal development because H...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Boulay, Gaylor, Dubuissez, Marion, Van Rechem, Capucine, Forget, Antoine, Helin, Kristian, Ayrault, Olivier, Leprince, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323039/
https://ncbi.nlm.nih.gov/pubmed/22315224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.320234
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados