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Mapping Human Protease-activated Receptor 4 (PAR4) Homodimer Interface to Transmembrane Helix 4

Thrombin activates platelets by binding and cleaving protease-activated receptors 1 and 4 (PAR1 and PAR4). Because of the importance of PAR4 activation on platelets in humans and mice and emerging roles for PAR4 in other tissues, experiments were done to characterize the interaction between PAR4 hom...

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Bibliografski detalji
Glavni autori: de la Fuente, María, Noble, Daniel N., Verma, Sheetal, Nieman, Marvin T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322995/
https://ncbi.nlm.nih.gov/pubmed/22318735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341438
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