C. elegans MCM-4 is a general DNA replication and checkpoint component with an epidermis-specific requirement for growth and viability

DNA replication and its connection to M phase restraint are studied extensively at the level of single cells but rarely in the context of a developing animal. C. elegans lin-6 mutants lack DNA synthesis in postembryonic somatic cell lineages, while entry into mitosis continues. These mutants grow sl...

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Hlavní autoři: Korzelius, Jerome, The, Inge, Ruijtenberg, Suzan, Portegijs, Vincent, Xu, Huihong, Horvitz, H. Robert, van den Heuvel, Sander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322639/
https://ncbi.nlm.nih.gov/pubmed/21146520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.12.009
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