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Coordinating cell proliferation and differentiation: Antagonism between cell cycle regulators and cell type-specific gene expression

Cell proliferation and differentiation show a remarkable inverse relationship. Precursor cells continue division before acquiring a fully differentiated state, while terminal differentiation usually coincides with proliferation arrest and permanent exit from the division cycle. Mechanistic insight i...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Ruijtenberg, Suzan, van den Heuvel, Sander
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825819/
https://ncbi.nlm.nih.gov/pubmed/26825227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1120925
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