Caenorhabditis elegans Cyclin D/CDK4 and Cyclin E/CDK2 Induce Distinct Cell Cycle Re-Entry Programs in Differentiated Muscle Cells

Cell proliferation and differentiation are regulated in a highly coordinated and inverse manner during development and tissue homeostasis. Terminal differentiation usually coincides with cell cycle exit and is thought to engage stable transcriptional repression of cell cycle genes. Here, we examine...

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Detalhes bibliográficos
Main Authors: Korzelius, Jerome, The, Inge, Ruijtenberg, Suzan, Prinsen, Martine B. W., Portegijs, Vincent, Middelkoop, Teije C., Groot Koerkamp, Marian J., Holstege, Frank C. P., Boxem, Mike, van den Heuvel, Sander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213155/
https://ncbi.nlm.nih.gov/pubmed/22102824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002362
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