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C. elegans MCM-4 is a general DNA replication and checkpoint component with an epidermis-specific requirement for growth and viability
DNA replication and its connection to M phase restraint are studied extensively at the level of single cells but rarely in the context of a developing animal. C. elegans lin-6 mutants lack DNA synthesis in postembryonic somatic cell lineages, while entry into mitosis continues. These mutants grow sl...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322639/ https://ncbi.nlm.nih.gov/pubmed/21146520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.12.009 |
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