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Preclinical evaluation of combined antineoplastic effect of DLC1 tumor suppressor protein and suberoylanilide hydroxamic acid on prostate cancer cells

Deleted in liver cancer (DLC1), a tumor suppressor gene in multiple cancers, is recurrently down regulated or inactivated by epigenetic mechanisms in primary prostate carcinomas (PCAs). In this study the methylation and acetylation profile of the DLC1 promoter region was examined in three PCA cell l...

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Bibliografiske detaljer
Main Authors: Zhou, Xiaoling, Yang, Xu-Yu, Popescu, Nicholas C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322246/
https://ncbi.nlm.nih.gov/pubmed/22425986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.02.158
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