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Pharmacokinetics and Pharmacodynamics of SuberoylanilideHydroxamic Acid in Cats

Suberoylanilidehydroxamic acid (SAHA), or vorinostat, is a histone deacetylase inhibitor approved for use as chemotherapy for lymphoma in humans. The goal of this study was to establish pharmacological parameters of SAHA in cats. Our interest in treating cats with SAHA is two-fold: as an anti-cancer...

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Detalhes bibliográficos
Main Authors: McDonnel, Samantha J, Tell, Lisa A, Murphy, Brian G
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949138/
https://ncbi.nlm.nih.gov/pubmed/24236915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvp.12088
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