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Pharmacokinetics and Pharmacodynamics of SuberoylanilideHydroxamic Acid in Cats

Suberoylanilidehydroxamic acid (SAHA), or vorinostat, is a histone deacetylase inhibitor approved for use as chemotherapy for lymphoma in humans. The goal of this study was to establish pharmacological parameters of SAHA in cats. Our interest in treating cats with SAHA is two-fold: as an anti-cancer...

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Hlavní autoři: McDonnel, Samantha J, Tell, Lisa A, Murphy, Brian G
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949138/
https://ncbi.nlm.nih.gov/pubmed/24236915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvp.12088
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