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Preclinical evaluation of combined antineoplastic effect of DLC1 tumor suppressor protein and suberoylanilide hydroxamic acid on prostate cancer cells

Deleted in liver cancer (DLC1), a tumor suppressor gene in multiple cancers, is recurrently down regulated or inactivated by epigenetic mechanisms in primary prostate carcinomas (PCAs). In this study the methylation and acetylation profile of the DLC1 promoter region was examined in three PCA cell l...

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Detalhes bibliográficos
Main Authors: Zhou, Xiaoling, Yang, Xu-Yu, Popescu, Nicholas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322246/
https://ncbi.nlm.nih.gov/pubmed/22425986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.02.158
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