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Targeting Protein Lipidation in Disease
Fatty acids and/or isoprenoids are covalently attached to a variety of disease-related proteins. The distinct chemical properties of each of these hydrophobic moieties allow lipid modification to serve as a mechanism to regulate protein structure, localization and function. This review highlights re...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322242/ https://ncbi.nlm.nih.gov/pubmed/22342806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.01.007 |
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