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Targeting Protein Lipidation in Disease

Fatty acids and/or isoprenoids are covalently attached to a variety of disease-related proteins. The distinct chemical properties of each of these hydrophobic moieties allow lipid modification to serve as a mechanism to regulate protein structure, localization and function. This review highlights re...

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Autore principale: Resh, Marilyn D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322242/
https://ncbi.nlm.nih.gov/pubmed/22342806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.01.007
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