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Linkage-Disequilibrium-Based Binning Affects the Interpretation of GWASs
Genome-wide association studies (GWASs) are critically dependent on detailed knowledge of the pattern of linkage disequilibrium (LD) in the human genome. GWASs generate lists of variants, usually SNPs, ranked according to the significance of their association to a trait. Downstream analyses generall...
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322240/ https://ncbi.nlm.nih.gov/pubmed/22444669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.02.025 |
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