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Linkage-Disequilibrium-Based Binning Affects the Interpretation of GWASs

Genome-wide association studies (GWASs) are critically dependent on detailed knowledge of the pattern of linkage disequilibrium (LD) in the human genome. GWASs generate lists of variants, usually SNPs, ranked according to the significance of their association to a trait. Downstream analyses generall...

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Detaylı Bibliyografya
Asıl Yazarlar: Christoforou, Andrea, Dondrup, Michael, Mattingsdal, Morten, Mattheisen, Manuel, Giddaluru, Sudheer, Nöthen, Markus M., Rietschel, Marcella, Cichon, Sven, Djurovic, Srdjan, Andreassen, Ole A., Jonassen, Inge, Steen, Vidar M., Puntervoll, Pål, Le Hellard, Stéphanie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322240/
https://ncbi.nlm.nih.gov/pubmed/22444669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.02.025
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