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Linkage-Disequilibrium-Based Binning Affects the Interpretation of GWASs
Genome-wide association studies (GWASs) are critically dependent on detailed knowledge of the pattern of linkage disequilibrium (LD) in the human genome. GWASs generate lists of variants, usually SNPs, ranked according to the significance of their association to a trait. Downstream analyses generall...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322240/ https://ncbi.nlm.nih.gov/pubmed/22444669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.02.025 |
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