Evidence that Growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells

Donor-matched transplantation of hematopoietic stem cells (HSCs) is widely used to treat hematologic malignancies but is associated with high mortality. The expansion of HSC numbers and their mobilization into the bloodstream could significantly improve therapy. We report here that adult mice condit...

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Autori principali: Khandanpour, Cyrus, Sharif-Askari, Ehssan, Vassen, Lothar, Gaudreau, Marie-Claude, Zhu, Jinfang, Paul, William E., Okayama, Taro, Kosan, Christian, Möröy, Tarik
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321835/
https://ncbi.nlm.nih.gov/pubmed/20826720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-280305
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