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Retroviral Insertional Mutagenesis Can Contribute to Immortalization of Mature T Lymphocytes
Several cases of T-cell leukemia caused by gammaretroviral insertional mutagenesis in children treated for x-linked severe combined immunodeficiency (SCID) by transplantation of autologous gene-modified stem cells were reported. In a comparative analysis, we recently showed that mature T cells, on t...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
ScholarOne
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321800/ https://ncbi.nlm.nih.gov/pubmed/21826372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00193 |
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