Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy

Cancer stem cell (SC) chemoresistance may be responsible for the poor clinical outcome of non-small-cell lung cancer (NSCLC) patients. In order to identify the molecular events that contribute to NSCLC chemoresistance, we investigated the DNA damage response in SCs derived from NSCLC patients. We fo...

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Detalhes bibliográficos
Main Authors: Bartucci, M, Svensson, S, Romania, P, Dattilo, R, Patrizii, M, Signore, M, Navarra, S, Lotti, F, Biffoni, M, Pilozzi, E, Duranti, E, Martinelli, S, Rinaldo, C, Zeuner, A, Maugeri-Saccà, M, Eramo, A, De Maria, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321626/
https://ncbi.nlm.nih.gov/pubmed/22117197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.170
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