Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy

Cancer stem cell (SC) chemoresistance may be responsible for the poor clinical outcome of non-small-cell lung cancer (NSCLC) patients. In order to identify the molecular events that contribute to NSCLC chemoresistance, we investigated the DNA damage response in SCs derived from NSCLC patients. We fo...

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Bibliographische Detailangaben
Hauptverfasser: Bartucci, M, Svensson, S, Romania, P, Dattilo, R, Patrizii, M, Signore, M, Navarra, S, Lotti, F, Biffoni, M, Pilozzi, E, Duranti, E, Martinelli, S, Rinaldo, C, Zeuner, A, Maugeri-Saccà, M, Eramo, A, De Maria, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321626/
https://ncbi.nlm.nih.gov/pubmed/22117197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.170
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