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Structural and Thermodynamic Comparison of the Catalytic Domain of AMSH and AMSH-LP: Nearly Identical Fold but Different Stability
AMSH plays a critical role in the endosomal sorting complexes required for transport (ESCRT) machinery, which facilitates the down-regulation and degradation of cell-surface receptors. It displays a high level of specificity towards cleavage of Lys63-linked polyubiquitin chain, the structural basis...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321355/ https://ncbi.nlm.nih.gov/pubmed/21888914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.08.029 |
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