Antisense pro-drugs: 5'-ester oligodeoxynucleotides.

Oligonucleotides bearing a terminal lipophilic group attached through a biodegradable ester bond should be useful as antisense pro-drugs with improved cellular uptake. The synthesis of 5'-ester oligonucleotides is, however, problematic due to lability of the ester bond during aqueous ammonia treatme...

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Xehetasun bibliografikoak

Argitaratua izan da:	Nucleic Acids Res
Egile Nagusiak:	Polushin, N N, Cohen, J S
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Oxford University Press 1994
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332106/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.24.5492
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