Antisense pro-drugs: 5'-ester oligodeoxynucleotides.
Oligonucleotides bearing a terminal lipophilic group attached through a biodegradable ester bond should be useful as antisense pro-drugs with improved cellular uptake. The synthesis of 5'-ester oligonucleotides is, however, problematic due to lability of the ester bond during aqueous ammonia treatme...
Na minha lista:
| Udgivet i: | Nucleic Acids Res |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1994
|
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332106/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.24.5492 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|