Inhibition of human immunodeficiency virus in early infected and chronically infected cells by antisense oligodeoxynucleotides and their phosphorothioate analogues.

Antisense oligodeoxynucleotides, both the phosphorothioate analogues and unmodified oligomers of the same sequence, inhibit replication and expression of human immunodeficiency virus already growing in tissue cultures of MOLT-3 cells with much greater efficacy than do mismatched ("random")...

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Bibliographic Details
Main Authors: Agrawal, S, Ikeuchi, T, Sun, D, Sarin, P S, Konopka, A, Maizel, J, Zamecnik, P C
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC298156/
https://ncbi.nlm.nih.gov/pubmed/2682627
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