Inhibition of human immunodeficiency virus in early infected and chronically infected cells by antisense oligodeoxynucleotides and their phosphorothioate analogues.

Antisense oligodeoxynucleotides, both the phosphorothioate analogues and unmodified oligomers of the same sequence, inhibit replication and expression of human immunodeficiency virus already growing in tissue cultures of MOLT-3 cells with much greater efficacy than do mismatched ("random")...

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Autors principals: Agrawal, S, Ikeuchi, T, Sun, D, Sarin, P S, Konopka, A, Maizel, J, Zamecnik, P C
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC298156/
https://ncbi.nlm.nih.gov/pubmed/2682627
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