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c-Jun and Ets2 Proteins Regulate Expression of Spleen Tyrosine Kinase in T Cells
Effector T cells and T cells from patients with systemic lupus erythematosus (SLE) express increased levels of the spleen tyrosine kinase (Syk). Syk binds to the T cell receptor (TCR)-CD3 complex and transduces the TCR-mediated signal in the cell more efficiently than the canonical CD3ζ chain. The r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320931/ https://ncbi.nlm.nih.gov/pubmed/22354960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.333997 |
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