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c-Jun and Ets2 Proteins Regulate Expression of Spleen Tyrosine Kinase in T Cells

Effector T cells and T cells from patients with systemic lupus erythematosus (SLE) express increased levels of the spleen tyrosine kinase (Syk). Syk binds to the T cell receptor (TCR)-CD3 complex and transduces the TCR-mediated signal in the cell more efficiently than the canonical CD3ζ chain. The r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ghosh, Debjani, Tsokos, George C., Kyttaris, Vasileios C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320931/
https://ncbi.nlm.nih.gov/pubmed/22354960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.333997
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